Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study.

Authors: Grosse-Sundrup M, Henneman JP, Sandberg WS, Bateman BT, Uribe JV, Nguyen NT, Ehrenfeld JM, Martinez EA, Kurth T, Eikermann M.

Tens of millions of people worldwide undergo general anesthesia every day. Anesthetists use a wide variety of drugs to establish the reversible state of anesthesia, which is characterised by hypnosis, amnesia, analgesia, hemodynamic stability with control of the stress response, and immobility. Deep anesthesia provides all components; however, to achieve immobility with lower levels of anesthetic agents, anesthetists may coadminister curare-type neuromuscular blocking agents.

read more…

Sonja Schmidt