Migraine and breast cancer risk: a prospective cohort study and meta-analysis.
Authors: Winter AC, Rice MS, Fortner RT, Eliassen AH, Kurth T, Tamimi RM.
Migraine, a common primary headache disorder, is a heterogeneous disease primarily affecting women. There is increasing evidence that migraine is linked to diverse comorbidities, and an association between migraine and breast cancer has been proposed. In two large case-control studies, migraineurs had a 26% to 33% lower risk of invasive breast cancer and a prospective cohort study suggested a more modest 11% lower risk. However, a recently published large prospective cohort study did not observe an association